Necrolytic migratory erythema in a patient with neuroendocrine carcinoma.
نویسندگان
چکیده
Necrolytic migratory erythema is an obligatory paraneoplastic syndrome. Here we describe a patient with a neuroendocrine tumor of probably pancreatic origin. She developed the typical skin lesions under chemotherapy with temozolomide and capecitabine.
منابع مشابه
Necrolytic migratory erythema associated with glucagonoma syndrome: a case report.
Necrolytic migratory erythema is a rare skin condition that consists of migrating areas of erythema with blisters that heal with hyperpigmentation. It usually occurs in patients with an alpha islet cell tumor of the pancreas-or glucagonoma-and when associated with glucose intolerance, anemia, hyperglucagonemia, and weight loss defines the glucagonoma syndrome. We describe a 52-year-old female p...
متن کاملGlucagonoma syndrome associated with necrolytic migratory erythema.
INTRODUCTION glucagonoma is a pancreatic neuroendocrine tumor derived from alpha-cells of the islets of Langerhans. It is marked by tumoral autonomous production of glucagon and characterized, among other symptoms, by necrolytic migratory erythema, an erythematous circinate lesion with areas of necrosis and sloughing. This is a rare disease with worldwide incidence estimated at 1 case per 20 mi...
متن کاملPropionic acidemia and zinc deficiency presenting as necrolytic migratory erythema.
Necrolytic migratory erythema was first described in 1942 in a patient with pancreatic islet cell carcinoma. The disease can, however, have other etiologies including nutritional dermatoses. Here, we describe the clinicopathological picture of a 7-year-old female patient who presented with necrolytic migratory erythema which we believe is secondary to a rare combination of zinc deficiency and p...
متن کاملNecrolytic migratory erythema associated with hyperglucagonemia and neuroendocrine hepatic tumors.
We present a 61-year-old man with a 2-year history of persistent disseminated, psoriasiform annular pruritic lesions, acrodermatitis, weight loss, anemia and diabetes. Histopathology of the affected skin showed nonspecific subacute psoriasiform dermatitis. The computed tomographic scan of the abdomen revealed multiple hepatic tumors. Histopathological examination of ultrasound-guided needle bio...
متن کاملNecrolytic Migratory Erythema Associated with Glucagonoma: A Report of 2 Cases
Glucagonoma syndrome is a rare disease that is usually associated with an underlying neuroendocrine tumor. Necrolytic Migratory Erythema (NME) has been associated with intestinal malabsorption disorders, hepatic cirrhosis, chronic pancreatitis, inflammatory bowel disease, and non-pancreatic malignancies, but may not always be associated with glucagonoma. In 1979, Mallinson and co-workers coined...
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ورودعنوان ژورنال:
- Internal medicine
دوره 52 1 شماره
صفحات -
تاریخ انتشار 2013